Advanced Application Technologies to Boost Big Data Utilization for Multiple-Field Scientific Discovery and Social Problem Solving

Detecting premonitory signs and real-time forecasting of pandemic using big biological data
Detecting premonitory signs and real-time forecasting of pandemic using big biological data

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Principle researchers

h_nishiuraName: Hiroshi Nishiura
Affiliation: Graduate School of Medicine, Hokkaido University
Position: Professor
Responsibility: Project manager, Infectious disease modelling using a large-scale data

Academic history:
2016-present Professor, Department of Hygiene, Graduate School of Medicine, Hokkaido University, Japan
2013-2016 Associate Professor, Department of Global Health Policy, The University of Tokyo, Japan
2011-2013 Assistant management professor, School of Public Health, The University of Hong Kong, China
2007-2011 Postdoctoral Research Fellow, Theoretical Epidemiology, Utrecht University, The Netherlands・Principal Investigator, PRESTO project, Japan Science and Technology Agency
2005-2007 Researcher (Mitarbeiter), Department of Medical Biometry, University of Tubingen, Germany
2006PhD in Health Science (with specialization in Biostatistics), Hiroshima University Graduate School of Health Sciences, Japan
2002 MD, Miyazaki Medical College (University of Miyazaki School of Medicine), Japan


t_higuchiName: Tomoyuki Higuchi
Affiliation: The Institute of Statistical Mathematics (ISM)
Position: Director-General
Responsibility: Proposal
of efficient data assimilation technique

Academic history:
2011-present Director, Research and Development Center for Data Assimilation・Director-General, The Institute of Statistical Mathematics・Executive Director, Research Organization of Information and Systems, Japan
2004-2011 Vice Director-General, The Institute of Statistical Mathematics, Japan
2003- 2005 Director of Prediction and Knowledge Discovery Research Center, The Institute of Statistical Mathematics, Japan
2002-2005 Professor, Division of Systems Analysis, Department of Prediction and Control, The Institute of Statistical Mathematics, Japan
1994-2002 Associate Professor, Division of Statistical Prediction, Department of Prediction and Control, The Institute of Statistical Mathematics, Japan
1989-1994 Assistant Professor, Division of Statistical Prediction, Department of Prediction and Control, The Institute of Statistical Mathematics, Japan
1989 Ph.D in Department of Earth and Planetary Physics, The University of Tokyo, Japan


k_itoName: Kimihito Ito
Affiliation: Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University
Position: Professor
Responsibility: Biological information analysis of micro data, and application to analyzing epidemic dynamics.

Academic history:
2015- Professor, Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University
2007- Associate Professor, Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University
2005- Assistant Professor, Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University
2004- Assistant Professor, Graduate School of Information Science and Technology, Hokkaido University
2002- Research Associate, Graduate school of Engineering, Hokkaido University
1999- Lecturer, Graduate School, Faculty of Engineering, Hokkaido University
1999- Ph.D in Engineering, Graduate School of Engineering, Hokkaido University
Research introduction:
We have conducted a research of bioinformatics technology utilizing information science in epidemic prediction of zoonotic disease control. By analyzing the genetic information of the epidemic in the past influenza virus on a large scale, we have developed a technology to predict the future of the mutation. In this program I am in charge of the information science education in graduate school and I teach data analysis methods and biostatistics to analyze the factors associated with epidemic and occurrence of zoonotic infections. I aim to contribute to development of human resources in zoonotic disease control and chemical hazard protection with a broad insight and synthetic judgment, by introducing a research technique that has been cultivated in information science research into research and education in the veterinary medicine.


k_satoName: Kei Sato
Affiliation: Institute for Virus Research, Kyoto University
Position: Assistant Professor
Responsibility: Analysis of HIV infection dynamics, analysis of HIV-infected humanized mouse model

Academical history:
2016-present Lecturer/Associate Professor, Institute for Virus Research, Kyoto University
2015 July-October Visiting Scientist, MRC-University of Glasgow
2012-2016 Assistant Professor, Institute for Virus Research, Kyoto University
2010-2012 Project Associate Professor, Institute for Virus Research, Kyoto University
2010 Ph.D in Medicine, Graduate School of Medicine, Kyoto University
Research introduction:
Since human immunodeficiency virus (HIV) is an virus that causes AIDS only in humans, it was very difficult to reproduce and analyze the infectious pathology from animal models. We succeeded to produce the experimental animal model that can reproduce the HIV infection pathology and re-construct a human immune system, by using “humanized mouse (humanized mouse)” model. Employing this animal model, we are promoting the research of the mechanism that HIV can cause AIDS. The dramatic improvement of the experimental analysis technology in recent years has enabled us to acquire detailed and extensive experimental data. By mathematically analyzing experimental data obtained from the virological analysis, we are trying to quantitatively clarify “true” viral infection dynamics that cannot be found from subjective point of view. We have done joint researches conducted by several types of virologists and mathematicians and have developed cross-disciplinary researches, which is called systemic viral infection, in order to elucidate infection dynamics of Influenza virus, Ebola virus and Hepatitis virus.


 

The Institute of Statistical Mathematics (ISM) Group

m_saitoName: Masaya Saito
Affiliation: Research and Development Center for Data Assimilation
Position: Program Associate Professor
Responsibility: Data assimilation using the parallel computer

Academic history:
2015-present Project Associate Professor, Research and Development Center for Data Assimilation, The Institute of Statistical Mathematics
2015 Project Assistant Professor, Graduate School of Medicine, The University of Tokyo
2012 Project Assistant Professor, Research and Development Center for Data Assimilation, The Institute of Statistical Mathematics
2009 Project researcher, Research and Development Center for Data Assimilation, The Institute of Statistical Mathematics
2008 Researcher, Japan Science and Technology Agency, CREST
2006 Researcher, Research Center for Verification and Semantics, National Institute of Advanced Industrial Science and Technology
2005 Ph.D. in Astronomical Science, The Graduate University of Advanced Studies.
Research introduction:
We apply sequential Bayesian filter in mathematical models, to estimate epidemics, and to evaluate interventions using cost-effective analysis. Mathematical models of infectious diseases have a strong non-linearity, and for such situation we cannot avoid Monte Carlo-based approach which needs large calculation. By taking the advantage of the use of the super computer “A” owned in the Research and Development Center for Data Assimilation in the Institute of Statistical Mathematics, we are developing an environment to allow high amount of calculation in the usage of tackling mathematical models of infectious diseases under ordinary circumstances.


white_imgName: Shinya Nakano
Affiliation: The Institute of Statistical Mathematics
Position: Assistant Professor
Responsibility: Mathematical modelling and Data assimilation


y_ariyoshiName: Yuya Ariyoshi
Affiliation: The Institute of Statistical Mathematics
Position: Project researcher
Responsibility: Mathematical modelling and Data assimilation


white_imgName: Nobuko Fujihara
Affiliation: The Institute of Statistical Mathematics
Position: Technical assistant
Responsibility: Research administrative and research assistant work


 

Kyoto University, Sato Group

k_watashiName: Koichi Watashi
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Senior Researcher
Responsibility: Analysis of Hepatitis virus


t_nodaName: Takeshi Noda
Affiliation: Institute for Virus Research, Kyoto University
Position: Professor
Responsibility: Analysis of the growth mechanism of Influenza virus and Ebola virus


s_moritaName: Satoru Morita
Affiliation: Department of Mathematical and Systems Engineering, Shizuoka University
Position: Associate Professor
Responsibility: Mathematical modeling, numerical calculation and statistical analysis


s_iwamiName: Shingo Iwami
Affiliation: Department of Biology, Kyushu University
Position: Associate Professor
Responsibility: Mathematical modeling, numerical calculation and statistical analysis


h_inabaName: Hisashi Inaba
Affiliation: Graduate School of Mathematical Sciences, The University of Tokyo
Position: Professor
Responsibility: Mathematical modeling


y_nakaoName: Yusuke Nakano
Affiliation: Institute for Virus Research, Kyoto University
Position: Postdoctoral researcher
Responsibility: Analysis of HIV infection dynamics


e_yamadaName: Eri Yamada
Affiliation: Institute for Virus Research, Kyoto University
Position: Doctoral student
Responsibility: Analysis of HIV infection dynamics


m_moriwakiName: Miyu Moriwaki
Affiliation: Institute for Virus Research, Kyoto University
Position: Master student
Responsibility: Analysis of HIV infection dynamics


m_nakanoName: Masahiro Nakano
Affiliation: Institute for Virus Research, Kyoto University
Position: Program researcher
Responsibility: Analysis of the growth mechanism of influenza virus


y_muramotoName: Yukiko Muramoto
Affiliation: Institute for Virus Research, Kyoto University
Position: Program researcher
Responsibility: Pathogenic analysis of influenza virus, highly pathogenic avian influenza virus


k_shindoName: Keiko Shindo
Affiliation: Institute for Virus Research, Kyoto University
Position: Program researcher
Responsibility: Analysis of the growth mechanism of influenza virus


s_tsukudaName: Senko Tsukuda
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Collaboration Researcher
Responsibility: Analysis of Hepatitis virus


m_iwamotoName: Masashi Iwamoto
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Research student
Responsibility: Analysis of Hepatitis virus


k_fukanoName: Kento Fukano
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Research student
Responsibility: Analysis of Hepatitis virus


h_ohashiName: Hirofumi Ohashi
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Research student
Responsibility: Analysis of Hepatitis virus and Dengue virus


m_kanekoName: Manabu Kaneko
Affiliation: Department of Virology Ⅱ, National Institute of Infectious Diseases
Position: Research student
Responsibility: Analysis of Hepatitis virus and fieldwork


y_kakizoeName: Yusuke Kakizoe
Affiliation: Graduate school of systems life sciences, Kyusyu University
Position: Doctoral student
Responsibility: Data analysis


y_itoName: Yusuke Ito
Affiliation: Graduate school of systems life sciences, Kyusyu University
Position: Doctoral student
Responsibility: Data analysis


t_funoName: Takaaki Funo
Affiliation: Graduate school of systems life sciences, Kyusyu University
Position: Doctoral student
Responsibility: Computer simulation


y_koizumiName: Yoshiki Koizumi
Affiliation: Graduate School of Medical sciences, Kanazawa University
Position: Medical student
Responsibility: Mathematical modelling


s_iwanamiName: Shoya Iwanami
Affiliation: Graduate school of systems life sciences, Kyusyu University
Position: Doctoral student
Responsibility: Probability simulation


 

Hokkaido University, Ito Group

white_imgName: Akira Sakai
Affiliation: Department of Mathematics, Hokkaido University
Position: Associate professor
Responsibility: Mathematical analysis of infectious disease epidemic model


d_higginsName: Des Higgins
Affiliation: Conway Institute of Biomolecular and Biomedical Science, University College Dublin
Position: Professor
Responsibility: Analysis of genetic information for infectious disease pathogen


r_omoriName: Ryosuke Omori
Affiliation: Division of Bioinformatics, Research Center for Zoonosis Control, Hokkaido University
Position: Assistant Professor
Responsibility: Analysis of infection transmission network


 

Hokkaido University, Nishiura Group

k_mizumotoName: Kenji Mizumoto
Affiliation: Department of Hygiene, Graduate School of Medicine, Hokkaido University
Position: Program Assistant Professor
Responsibility: Implementation of epidemiological models and genetics model


r_kinoshitaName: Ryo Kinoshita
Affiliation: Department of Hygiene, Graduate School of Medicine, Hokkaido University
Position: Doctoral Student, Research Assistant
Responsibility: Programming of parallel computation and mathematical model implementation


k_nahName: Kyeongah Nah
Affiliation: Department of Hygiene, Graduate School of Medicine, Hokkaido University
Position: Program Assistant Professor
Responsibility: Predictive model building accounting for human movement


y_asaiName: Yusuke Asai
Affiliation: Department of Hygiene, Graduate School of Medicine, Hokkaido University
Position: Assistant Professor
Responsibility: Predictive model building accounting for human movement


r_matsuyamaName: Ryota Matsuyama
Affiliation: Department of Hygiene, Graduate School of Medicine, Hokkaido University
Position: Postdoctoral Researcher
Responsibility: Predictive model building accounting for human movement


s_nakaokaName: Shinji Nakaoka
Affiliation: Institute of Industrial Science, The University of Tokyo
Position: Project Assistant Professor
Responsibility: Predictive model building accounting for human movement


  • JST
  • CREST
  • ISM
  • KYOTO UNIVERSITY
  • HOKKAIDO UNIVERCITY Research Center for Zoonosis Control
  • HOKKAIDO UNIVERCITY Graduate School ob Medicine School ob Medicine
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