Unification of laboratory virology and mathematical sciences in research
Our main focus of research is on influenza virus, AIDS virus, and hepatitis virus, by incorporating both laboratory virology and mathematical sciences as an interdisciplinary approach. Detailed laboratory data is obtained to be analyzed using mathematical sciences, and with the feedback of the two fields, various virus infection dynamics can be assessed and analyzed quantitatively from different aspects.
The following is a video of the T cell of a lymph node from a humanized mouse captured using Two-photon excitation microscopy. Using this microscope, cell kinetic of in vivo can be analyzed and quantified in four dimension (three dimension + time). We aim to directly interpret how the behavioral changes when virus infection in the cell happens, and quantitatively understand the mechanism.